CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Armed oncolytic measles vaccine virus – a novel therapeutic agent for virotherapy of solid tumors
DOI 10.1055/s-0031-1285441
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Autor:innenS Berchtold, J Lampe, T Weiland, S Schleicher, R Handgretinger, HG Kopp, J Reiser, F Stubenrauch, M Bitzer, UM Lauer
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2011
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: The oncolytic potential of measles vaccine virus (MeV) has been demonstrated in several tumor models but it has also been shown that primary and secondary resistances exist or may arise. To improve the oncolytic potential of MeV and to overcome resistances, a transgene armed measles vaccine virus was generated (MeV ld-SCD). A suicide gene (SCD) was inserted encoding a fusion protein consisting of the e…
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Zitierempfehlung
S Berchtold, J Lampe, T Weiland, S Schleicher, R Handgretinger, HG Kopp, J Reiser, F Stubenrauch, M Bitzer, UM Lauer (2011) Armed oncolytic measles vaccine virus – a novel therapeutic agent for virotherapy of solid tumors. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0031-1285441
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