CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Activation of constitutively active NFATc1 in murine pancreas triggers cellular apoptosis: a powerful and effective innate restraint to NFAT-induced tumorigenesis
DOI 10.1055/s-0031-1285537
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Autor:innenSK Singh, S Kernig, D Yazici, K Reutlinger, TM Gress, V Ellenrieder
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2011
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Introduction: The nuclear factor of activated T cells (NFAT) family of transcription factors has recently been implicated with a role in tumorigenesis. Forced expression of a constitutively active NFATc1 mutant (c.a.NFATc1) has been shown to transform immortalized murine fibroblasts in vitro, while constitutive activation of the NFAT-signaling pathway has been found in a number of human cancers, where it has been sh…
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Zitierempfehlung
SK Singh, S Kernig, D Yazici, K Reutlinger, TM Gress, V Ellenrieder (2011) Activation of constitutively active NFATc1 in murine pancreas triggers cellular apoptosis: a powerful and effective innate restraint to NFAT-induced tumorigenesis. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0031-1285537
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