CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Tumor selective miRNome modulation upon SAHA treatment in hepatocellular carcinoma
DOI 10.1055/s-0031-1285575
Bibliografische Angaben
Nachweis in CareLit
Autor:innenT Weiland, E Schwab, S Venturelli, A Berger, TS Weiss, M Bonin, UM Lauer, M Bitzer
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2011
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Epigenetic aberrations, including histone hypoacetylation, substantially contribute to initiation and progression of hepatocellular carcinoma (HCC). Newly developed drugs targeting epigenetic regulatory mechanisms, such as histone deacetylase inhibitors (HDACi), are available to reverse this contribution to the malignant phenotype of cancer cells. As a disease model in HCC e.g. the HDACi suberoylanilide hydroxamic a…
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Zitierempfehlung
T Weiland, E Schwab, S Venturelli, A Berger, TS Weiss, M Bonin, UM Lauer, M Bitzer (2011) Tumor selective miRNome modulation upon SAHA treatment in hepatocellular carcinoma. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0031-1285575
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