CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Migration of hepatic CXCR4+ fibrocytes is directed by SDF-1 in Abcb4-/- mice
DOI 10.1055/s-0031-1285713
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Autor:innenS Pasupuleti, C Neumann, A Tschuschner, E Roeb, M Roderfeld
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2011
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: CXCR4 chemokine receptor plays a central role in mobilization and homing of stem cells. Its ligand SDF-1 (stromal derived factor-1, CXCL12) creates the gradient required for directed migration of bone marrow derived CXCR4+ fibrocytes in different organ diseases1. Recently we could show that CD34+ bone marrow derived fibrocytes play a crucial role in hepatic fibrogenesis in the BALB/c-ABCB4 -/- mouse mo…
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Zitierempfehlung
S Pasupuleti, C Neumann, A Tschuschner, E Roeb, M Roderfeld (2011) Migration of hepatic CXCR4+ fibrocytes is directed by SDF-1 in Abcb4-/- mice. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0031-1285713
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