CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Ethanol sensitizes primary mouse hepatocytes for the apoptotic effects of transforming growth factor (TGF)-β
DOI 10.1055/s-0031-1285723
Bibliografische Angaben
Nachweis in CareLit
Autor:innenK Breitkopf-Heinlein, H Gaitantzi, C Meyer, Q Li, J Dzieran, S Schneider, A Müller, G Millonig, S Mueller, H Bantel, K Wahl, S Dooley
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2011
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
We previously showed that TGF-β signalling is increased in ethanol fed mice and that a combination of ethanol plus TGF-β causes much more apoptosis of primary mouse hepatocytes than each stimulus alone. In the present study we further analyzed this apoptosis induction and show that ethanol strongly enhances TGF-β Smad-signalling in isolated hepatocytes. Apoptosis induction was accompanied by reduced basal activity o…
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Zitierempfehlung
K Breitkopf-Heinlein, H Gaitantzi, C Meyer, Q Li, J Dzieran, S Schneider, A Müller, G Millonig, S Mueller, H Bantel, K Wahl, S Dooley (2011) Ethanol sensitizes primary mouse hepatocytes for the apoptotic effects of transforming growth factor (TGF)-β. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0031-1285723
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