CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Tracking genetic variation underlying differenzial reaction to TGF-beta signalling in inbred mouse strains
DOI 10.1055/s-0031-1285727
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Autor:innenR Müllenbach, I Ilkavets, S Dooley, F Lammert
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2011
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: TGF-β is the central pro-fibrogenic cytokine in the liver. In hepatocytes, cell death by apoptosis, growth arrest by cellular senescence or contribution towards healing by epithelial-mesenchymal transition are possible outcomes. We speculate that genetic differences underlying differences in response to TGF-β signalling may be involved in predisposition to fibrosis or hepatocellular carcinoma. Aims: Our…
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Zitierempfehlung
R Müllenbach, I Ilkavets, S Dooley, F Lammert (2011) Tracking genetic variation underlying differenzial reaction to TGF-beta signalling in inbred mouse strains. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0031-1285727
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