CareLit · DOI-Nachweis · Klinische Pädiatrie
Fatty acid synthase (FAS-272) expression increases with rise of WHO-grade and serves as indicator for the malignant transformation in human gliomas.
DOI 10.1055/s-0031-1292585
Bibliografische Angaben
Nachweis in CareLit
Autor:innenP Duenisch, S Grube, R Kalff, R Bauer, C Ewald
ZeitschriftKlinische Pädiatrie
Ausgabe11/2011
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Purpose: Gliomas are highly invasive neuroepithelial tumors with a propensity of malignant transformation and still restricted treatment options. Fatty acid synthase is a cytosolic multifunctional polypeptid which plays an essential role in cell metabolism. It catalyses the conversion of dietary carbohydrates to fatty acids which are incorporated as phospholipids into the cell membrane. High expression levels of fat…
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Zitierempfehlung
P Duenisch, S Grube, R Kalff, R Bauer, C Ewald (2011) Fatty acid synthase (FAS-272) expression increases with rise of WHO-grade and serves as indicator for the malignant transformation in human gliomas. Klinische Pädiatrie (11). https://doi.org/10.1055/s-0031-1292585
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