CareLit · DOI-Nachweis · Geburtshilfe und Frauenheilkunde
The pivotal role of protein inhibitors of activated STATs (PIAS) in regulating trophoblastic functions
DOI 10.1055/s-0031-1292725
Bibliografische Angaben
Nachweis in CareLit
Autor:innenL Khachaturyan, T Poehlmann, M Weber, J Fitzgerald, E Schleussner, U Markert
ZeitschriftGeburtshilfe und Frauenheilkunde
Ausgabe11/2011
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: Signal Transducer and Activator of Transcription 3 (STAT3) is an intracellular signaling molecule which, in trophoblastic cells, can be phosphorylated at its tyr705 (p-STAT3 tyr705) residue by Leukemia Inhibitory Factor (LIF) receptor binding. This phosphorylation correlates with invasiveness. Protein inhibitors of activated STATs (PIAS) antagonize STAT function by interfering with STAT DNA-binding and a…
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Zitierempfehlung
L Khachaturyan, T Poehlmann, M Weber, J Fitzgerald, E Schleussner, U Markert (2011) The pivotal role of protein inhibitors of activated STATs (PIAS) in regulating trophoblastic functions. Geburtshilfe und Frauenheilkunde (11). https://doi.org/10.1055/s-0031-1292725
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