CareLit · DOI-Nachweis · Zeitschrift für Geburtshilfe und Neonatologie
Genetic Low Nephron Number Hypertension is Associated with Altered Expression of Osteopontin and One of Its Receptors, CD44, but not Alpha(v)-Integrin during Nephrogenesis
DOI 10.1055/s-0031-1293277
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Autor:innenAL Freese, M Wehland, F Freese, A Schulz, R Kreutz, L Rothermund
ZeitschriftZeitschrift für Geburtshilfe und Neonatologie
Ausgabe11/2011
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Ziel: Low nephron number may represent a major determinant of human primary hypertension in adult life. This hypothesis is supported by a genetic rat model, the Munich-Wistar Frömter (MWF) rat, which demonstrates an inherited deficit in nephron number and the development of spontaneous hypertension. Osteopontin and its receptors cd44 and alpha(v)beta(3)integrin play a role in growth and differentiation processes dur…
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Zitierempfehlung
AL Freese, M Wehland, F Freese, A Schulz, R Kreutz, L Rothermund (2011) Genetic Low Nephron Number Hypertension is Associated with Altered Expression of Osteopontin and One of Its Receptors, CD44, but not Alpha(v)-Integrin during Nephrogenesis. Zeitschrift für Geburtshilfe und Neonatologie (11). https://doi.org/10.1055/s-0031-1293277
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