CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Identification of phenotypic and expression quantitative trait loci (p/eQTLs) affecting liver fibrosis by genome-wide association analysis in recombinant inbred mouse lines
DOI 10.1055/s-0031-1295730
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Autor:innenR Hall, I Heim, S Huss, R Alberts, K Schughart, K Hochrath, SN Weber, R Müllenbach, RW Williams, F Lammert
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2012
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Aims: Liver fibrosis is a complex disease mediated by multiple interacting genes and environmental factors. Our aim is to identify genetic loci that confer susceptibility to liver fibrosis. We now induced fibrosis in the genetically well characterised reference panel of BXD recombinant inbred lines and linked differences in liver fibrosis to the genetic variation segregating among the lines. Methods: In total, 30 BX…
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Zitierempfehlung
R Hall, I Heim, S Huss, R Alberts, K Schughart, K Hochrath, SN Weber, R Müllenbach, RW Williams, F Lammert (2012) Identification of phenotypic and expression quantitative trait loci (p/eQTLs) affecting liver fibrosis by genome-wide association analysis in recombinant inbred mouse lines. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0031-1295730
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