CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Adenoviral expression of the Nephroblastoma overexpressed gene product (CCN3/NOV) induces apoptosis and inhibits epithelial-to-mesenchymal transition (EMT) in hepatocytes in vitro but fails to attenuate ongoing liver fibrogenesis in vivo
DOI 10.1055/s-0031-1295733
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Autor:innenE Borkham-Kamphorst, S Huss, E Van de Leur, U Haas, R Weiskirchen
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2012
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
CCN3/NOV encoded by the Nephroblastoma overexpressed gene represents a matricellular protein of the CCN family. These proteins comprise six different secreted proteins associating specifically with the extracellular matrix [1]. CCN proteins lack specific high-affinity receptors but signal through integrins and proteoglycans and regulate crucial biological processes in liver including fibrosis [2]. Previously we have…
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Zitierempfehlung
E Borkham-Kamphorst, S Huss, E Van de Leur, U Haas, R Weiskirchen (2012) Adenoviral expression of the Nephroblastoma overexpressed gene product (CCN3/NOV) induces apoptosis and inhibits epithelial-to-mesenchymal transition (EMT) in hepatocytes in vitro but fails to attenuate ongoing liver fibrogenesis in vivo. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0031-1295733
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