CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
JNK1 is protective for the progression of NEMO-dependent hepatitis
DOI 10.1055/s-0031-1295735
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Nachweis in CareLit
Autor:innenFJ Cubero, G Zhao, M Hatting, O Drvarov, Y Nevzorova, M Al Massoudi, N Gassler, C Liedtke, C Trautwein
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aims: Deletion of the regulatory subunit IKKγ/NEMO of NF-κB in hepatocytes (NEMOΔhepa) triggers chronic inflammation and spontaneous hepatocellular carcinoma (HCC). We have previously reported that JNK in NEMOΔhepa mice is chronically activated which suggests that the JNK signaling pathway is essential in the progression of the disease. Aims: to elucidate the role of JNK1 and JNK2 in the development of hepatitis, st…
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Zitierempfehlung
FJ Cubero, G Zhao, M Hatting, O Drvarov, Y Nevzorova, M Al Massoudi, N Gassler, C Liedtke, C Trautwein (2012) JNK1 is protective for the progression of NEMO-dependent hepatitis. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0031-1295735
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