Xanthohumol improves glucose tolerance and inhibits hepatic steatosis, inflammation and fibrogenesis in a murine model of non-alcoholic steatohepatitis

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Xanthohumol, the principal prenylated flavonoid of the female inflorescences of the hop plant, has been most extensively studied as cancer chemopreventive agent. In addition, anti-inflammatory properties have been demonstrated in various organs including the liver. Nonalcoholic fatty liver disease (NAFLD) is considered as hepatic manifestation of the metabolic syndrome, and in a subset of cases hepatic steatosis pro…

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