CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Cultivation of primary hepatocytes induces an inflammation-cholestasis response that resembles features of in vivo inflammation during damage and regeneration
DOI 10.1055/s-0031-1295742
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Autor:innenP Godoy, W Schmidt-Heck, A Widera, G Campos, R Guthke, R Gebhardt, M Arrese, S Dooley, R Reif, JG Hengstler
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Although is well known that cultivation of primary hepatocytes results in a dramatic loss of function and dedifferentiation with features of epithelial to mesenchymal transition, it is generally assumed that most of these alterations are largely repressed on 3D extracellular matrix. To gain a comprehensive insight on the alterations occurring in culture, we performed gene array analysis of primary mouse hepatocytes…
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Zitierempfehlung
P Godoy, W Schmidt-Heck, A Widera, G Campos, R Guthke, R Gebhardt, M Arrese, S Dooley, R Reif, JG Hengstler (2012) Cultivation of primary hepatocytes induces an inflammation-cholestasis response that resembles features of in vivo inflammation during damage and regeneration. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0031-1295742
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