CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
The chemokine receptor CCR8 critically controls hepatic macrophage migration and differentiation in murine liver fibrosis
DOI 10.1055/s-0031-1295747
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Autor:innenF Heymann, L Hammerich, N Gassler, T Luedde, C Trautwein, F Tacke
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2012
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Aims: Chemokines are important regulators of immune cell infiltration upon liver injury, thereby controlling hepatic inflammation and fibrosis. The chemokine receptor CCR8 can affect trafficking of monocytes/macrophages, monocyte-derived dendritic cells (DCs) and T helper cell subsets, but its role in liver diseases is currently unknown. Methods: ccr8-/- and wildtype (wt) mice were subjected to chronic experimental…
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Zitierempfehlung
F Heymann, L Hammerich, N Gassler, T Luedde, C Trautwein, F Tacke (2012) The chemokine receptor CCR8 critically controls hepatic macrophage migration and differentiation in murine liver fibrosis. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0031-1295747
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