CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Hepatic cytochrome P–4502E1 induction correlates significantly with the degree of steatosis, inflammation, fibrosis and exocyclic etheno DNA-adducts in patients with alcoholic steatohepatitis (ASH) and non-alcoholic fatty liver disease (NA…
DOI 10.1055/s-0031-1295749
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Nachweis in CareLit
Autor:innenQ Hua, K Glassen, R Waldherr, G Millonig, S Mueller, HK Seitz
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
It has been shown that cytochrome P402E1 (CYP2E1) is induced in alcoholic liver disease (ALD)1 and in non-alcoholic fatty liver disease (NAFLD)2. Hepatic CYP2E1 is responsible for the generation of reactive oxygen species (ROS) which may stimulate fibrogenesis and carcinogenesis since hepatic CYP2E1 correlates significantly with highly carcinogenic exocyclic etheno DNA-adducts (edA) 3. In experimental ALD inhibition…
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Zitierempfehlung
Q Hua, K Glassen, R Waldherr, G Millonig, S Mueller, HK Seitz (2012) Hepatic cytochrome P–4502E1 induction correlates significantly with the degree of steatosis, inflammation, fibrosis and exocyclic etheno DNA-adducts in patients with alcoholic steatohepatitis (ASH) and non-alcoholic fatty liver disease (NAFLD). Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0031-1295749
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