CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
TGF-beta mediates transcriptional repression of miR–29 a/b1 during liver fibrosis
DOI 10.1055/s-0031-1295750
Bibliografische Angaben
Nachweis in CareLit
Autor:innenJ Huang, N Elfimova, A Noetel, W Amer, M Kwiecinski, HP Dienes, H Peter, M Odenthal
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background and aim: microRNA(miRNA) are small noncoding RNAs that play an important role in post-transcriptional inhibition of gene expression. Recent studies identified miR–29 as an antifibrotic miRNA, regulating collagen–1 and –4 expression in hepatic stellate cells (HSC). Additionally, the members of the miR–29 family were shown to be downregulated in livers from patients with advanced hepatic fibrosis. In the pr…
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Zitierempfehlung
J Huang, N Elfimova, A Noetel, W Amer, M Kwiecinski, HP Dienes, H Peter, M Odenthal (2012) TGF-beta mediates transcriptional repression of miR–29 a/b1 during liver fibrosis. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0031-1295750
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