CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Identification of a novel genetic risk factor for liver fibrosis within the adiponutrin (PNPLA3) pathway: elastography-based study in patients with chronic liver diseases
DOI 10.1055/s-0031-1295756
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Autor:innenM Krawczyk, MG Mahler, F Lammert, F Grünhage
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aims: Lately we have identified the p.I148M adiponutrin (PNPLA3) variant as common genetic risk factor for liver fibrosis1. In humans, PNPLA3 expression is induced by sterol regulatory element binding protein 1c (SREBP1c). Here we investigate two SREBP1c variants (rs2297508 and rs11868035), recently associated with insulin resistance and diabetes2, as genetic determinants for hepatic fibrosis. Patients and methods:…
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Zitierempfehlung
M Krawczyk, MG Mahler, F Lammert, F Grünhage (2012) Identification of a novel genetic risk factor for liver fibrosis within the adiponutrin (PNPLA3) pathway: elastography-based study in patients with chronic liver diseases. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0031-1295756
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