CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Hepcidin knockout mice as a model of iron-overload associated liver fibrosis development
DOI 10.1055/s-0031-1295759
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Autor:innenM Lunova, S Vaulont, J Haybaeck, K Lackner, P Strnad
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2012
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Background and aims: Hepcidin is the central regulator of iron homeostasis. Disrupted hepcidin signalling results in hereditary hemochromatosis and iron overload in chronic liver disorders. While the association between iron overload and development of end-stage liver disease is well established, the understanding of the underlying pathomechanisms is hampered by the lack of a suitable animal model. To circumvent thi…
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Zitierempfehlung
M Lunova, S Vaulont, J Haybaeck, K Lackner, P Strnad (2012) Hepcidin knockout mice as a model of iron-overload associated liver fibrosis development. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0031-1295759
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