CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Inhibiting the oligomerisation and glycosaminoglycan binding of the chemokine CCL5 reduces experimental liver injury in vivo
DOI 10.1055/s-0031-1295768
Bibliografische Angaben
Nachweis in CareLit
Autor:innenA Nellen, D Heinrichs, M Moreno Zaldivar, P Fischer, ML Berres, A Proudfoot, C Trautwein, HE Wasmuth
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aims: We recently identified the chemokine CCL5 as a mediator of the interaction between immune cells and hepatic stellate cells. Notably, a competitive antagonist of CCL5 receptors ameliorated liver injury in vivo (Berres et al. JCI 2010). We here investigate whether inhibition of CCL5 oligomerisation and glycosaminoglycan binding by a mutated CCL5 protein (44AANA47-CCL5) does also ameliorate liver cell injury and…
Zitieren
Zitierempfehlung
A Nellen, D Heinrichs, M Moreno Zaldivar, P Fischer, ML Berres, A Proudfoot, C Trautwein, HE Wasmuth (2012) Inhibiting the oligomerisation and glycosaminoglycan binding of the chemokine CCL5 reduces experimental liver injury in vivo. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0031-1295768
Mit CareLit weiterarbeiten