CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Aging promotes hepatocellular steatosis, inflammation and fibrosis in non-alcoholic steatohepatitis in mice
DOI 10.1055/s-0031-1295778
Bibliografische Angaben
Nachweis in CareLit
Autor:innenM Saugspier, C Dorn, C Hellerbrand
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Nonalcoholic steatohepatitis involves necroinflammatory activity and fibrosis, which are believed to be mediated by lipotoxicity caused by toxic metabolites from excess fatty acids. Epidemiological studies indicate that age has impact on the natural course of NAFLD. The aim of this study was to assess whether there are age dependent differences in the susceptibility to lipotoxicity and NASH in primary hepatocytes an…
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Zitierempfehlung
M Saugspier, C Dorn, C Hellerbrand (2012) Aging promotes hepatocellular steatosis, inflammation and fibrosis in non-alcoholic steatohepatitis in mice. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0031-1295778
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