CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Antagonism of CCL5 chemokine receptors during regression of liver fibrosis is associated with an intrahepatic shift towards pro-inflammatory macrophages
DOI 10.1055/s-0031-1295782
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Nachweis in CareLit
Autor:innenMK Stock, L Hammerich, ML Berres, C Trautwein, F Tacke, HE Wasmuth
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aims: Chemokines mediate the progression but also the regression of liver fibrosis. We could recently show that antagonism of the chemokine CCL5 with Met-CCL5 accelerates the regression of liver fibrosis (Berres et al. JCI 2010). Here we aimed to investigate the underlying mechanisms for the faster resolution of liver scarring in this model. Methods: C57BL/6 mice were treated with CCl4 for eight weeks to induce seve…
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Zitierempfehlung
MK Stock, L Hammerich, ML Berres, C Trautwein, F Tacke, HE Wasmuth (2012) Antagonism of CCL5 chemokine receptors during regression of liver fibrosis is associated with an intrahepatic shift towards pro-inflammatory macrophages. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0031-1295782
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