CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
MMP–9 activity is increased by adiponectin in primary human hepatocytes but negatively correlates with serum adiponectin in a rodent model of non-alcoholic steatohepatitis
DOI 10.1055/s-0031-1295787
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Nachweis in CareLit
Autor:innenR Walter, J Wanninger, S Bauer, K Eisinger, A Schäffler, C Dorn, TS Weiss, C Hellerbrand, C Buechler
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Objective: Adiponectin protects from inflammation and fibrosis in metabolic liver disease. In the present study we analyzed whether this adipokine may directly affect the activity of matrix metalloproteinases (MMPs), central regulators of fibrinolysis, in hepatocytes. Methods: Primary human hepatocytes and liver of patients with and without liver steatosis were used. Human liver tissue was obtained according to the…
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Zitierempfehlung
R Walter, J Wanninger, S Bauer, K Eisinger, A Schäffler, C Dorn, TS Weiss, C Hellerbrand, C Buechler (2012) MMP–9 activity is increased by adiponectin in primary human hepatocytes but negatively correlates with serum adiponectin in a rodent model of non-alcoholic steatohepatitis. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0031-1295787
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