CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
HCV/TLR3 modulated the expression of RANTES in murine activated hepatic stellate cells
DOI 10.1055/s-0031-1295788
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Autor:innenB Wang, R Bröring, CI Real, M Trippler, G Gerken, M Lu, JF Schlaak
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2012
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Background/Aims: RANTES/CCL5 has been identified as a central mediator in liver fibrogenesis. However, the interaction between HCV/TLR3 and RANTES and its functional role for hepatic stellate cells (HSC) is not well understood. Methods: Wide-type and TLR3-/- mice were treated with TLR3 ligands (Poly I: C). The expression of hepatic RANTES and IFN-β was detected by quantitative real time RT-PCR (qrt-PCR). Primary HSC…
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Zitierempfehlung
B Wang, R Bröring, CI Real, M Trippler, G Gerken, M Lu, JF Schlaak (2012) HCV/TLR3 modulated the expression of RANTES in murine activated hepatic stellate cells. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0031-1295788
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