CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Analysis of cellular origin and degradation pathways of the endocannabinoid 2-arachidonoyl glycerol during liver fibrogenesis
DOI 10.1055/s-0031-1295793
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Autor:innenA Wojtalla, MV Singer, T Sauerbruch, A Zimmer, SV Siegmund
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
BACKGROUND and Aims: We and others have previously shown, that the hepatic endocannabinoid (EC) system becomes activated and plays an important role in liver fibrogenesis. However, cellular origin and mechanisms that lead to increased EC levels (e.g. 2-arachydonoyl glycerol, 2-AG) are unknown. We analysed expression of the major 2-AG-generating enzyme diacylglycerol lipase (DAGL)-beta and the main degrading enzyme m…
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Zitierempfehlung
A Wojtalla, MV Singer, T Sauerbruch, A Zimmer, SV Siegmund (2012) Analysis of cellular origin and degradation pathways of the endocannabinoid 2-arachidonoyl glycerol during liver fibrogenesis. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0031-1295793
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