CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
The role of Suppressor of Fused in the regulation of Hedgehog and Wnt/ß-Catenin signaling pathway in adult liver
DOI 10.1055/s-0031-1295799
Bibliografische Angaben
Nachweis in CareLit
Autor:innenS Aleithe, M Matz-Soja, R Gebhardt
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aims: Sufu is one of the most important regulatory elements that can negatively influence the Hedgehog signaling pathway, witch plays a critical role in cell differentiation and development of the liver. In the absence of Hedgehog signals, Sufu forms an inhibition complex with Fu and Cos2, causing a proteolytic cleavage of the transcription factors Gli2 and Gli3 into their repressor forms and so inhibiting the expre…
Zitieren
Zitierempfehlung
S Aleithe, M Matz-Soja, R Gebhardt (2012) The role of Suppressor of Fused in the regulation of Hedgehog and Wnt/ß-Catenin signaling pathway in adult liver. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0031-1295799
Mit CareLit weiterarbeiten