CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Non-canonical functions of Cyclin E1 for control of hepatic DNA replication and liver regeneration in mice
DOI 10.1055/s-0031-1295806
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Nachweis in CareLit
Autor:innenW Hu, YA Nevzorova, U Haas, P Sicinski, M Barbacid, C Trautwein, C Liedtke
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Canonical cell cycle activation in quiescent hepatocytes prior to liver regeneration involves complex formation of cyclin E1 (CcnE1) with its associated cyclin-dependent kinase 2 (Cdk2), thereby initiating DNA-replication (S-phase). Surprisingly, we previously found that unique loss of either Cdk2 or CcnE1 does not affect hepatocyte proliferation after partial hepatectomy (PH). Thus, the aim of the current study was…
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Zitierempfehlung
W Hu, YA Nevzorova, U Haas, P Sicinski, M Barbacid, C Trautwein, C Liedtke (2012) Non-canonical functions of Cyclin E1 for control of hepatic DNA replication and liver regeneration in mice. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0031-1295806
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