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In vitro and in vivo models for chemotherapy-associated steatohepatitis reveal an effect of irinotecan on fatty acid binding protein expression

A Mahli, M Saugspier, WE Thasler, C Hellerbrand · Zeitschrift für Gastroenterologie · Ausgabe 01/2012

DOI 10.1055/s-0031-1295815

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Autor:innenA Mahli, M Saugspier, WE Thasler, C Hellerbrand
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2012
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Preoperative chemotherapy with irinotecan is associated with the development of chemotherapy-associated steatohepatitis (CASH). This increases the risk of perioperative morbidity and mortality, however, the underlying mechanisms of irinotecan induced hepatic steatosis and inflammation are still unknown.The aim of this study was to establish in vitro and in vivo models of irinotecan induced CASH and to unravel the mo…

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A Mahli, M Saugspier, WE Thasler, C Hellerbrand (2012) In vitro and in vivo models for chemotherapy-associated steatohepatitis reveal an effect of irinotecan on fatty acid binding protein expression. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0031-1295815

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