CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Detection of highly carcinogenic, exocyclic etheno-DNA-adducts in the liver of children with non-alcoholic fatty liver disease
DOI 10.1055/s-0031-1295833
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Autor:innenU Teufel, G Engelmann, C Flechtenmacher, T Peccerella, G Millonig, G Hoffmann, S Mueller, HK Seitz
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2012
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Exocyclic etheno-DNA-adducts (edA) are highly carcinogenic DNA-lesions which are formed by the reaction of the lipid peroxidation product 4-hydroxynonenal (4HNE) with DNA 1. Recently, we found a significant correlation between the induction of cytochrome P4502E1 (CYP2E1) and edA in patients with alcoholic liver disease 2. CYP2E1 is also induced in non-alcoholic fatty liver disease (NAFLD) 3, a growing liver disease…
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Zitierempfehlung
U Teufel, G Engelmann, C Flechtenmacher, T Peccerella, G Millonig, G Hoffmann, S Mueller, HK Seitz (2012) Detection of highly carcinogenic, exocyclic etheno-DNA-adducts in the liver of children with non-alcoholic fatty liver disease. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0031-1295833
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