CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Entrapment of primary human hepatocytes in extracellular matrix gels for long term toxicity studies
DOI 10.1055/s-0031-1295862
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Nachweis in CareLit
Autor:innenJJ Martínez Sánchez, S Ehnert, AK Nüssler, X Yan, L Schyschka
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: During the last decade pharmaceutical companies aimed to develop strategies to reduce animal tests for drug screenings. Many of these new methods are based on the in vitro culture of primary human hepatocytes (hHeps), which rapidly lose their function under conventional culture conditions (2D). 3D cultures, mandatory to obtain their function, cannot be used for drug-testings due to their huge need for…
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Zitierempfehlung
JJ Martínez Sánchez, S Ehnert, AK Nüssler, X Yan, L Schyschka (2012) Entrapment of primary human hepatocytes in extracellular matrix gels for long term toxicity studies. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0031-1295862
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