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Protection against Cholestasis and Ischemia in vitro by Ursodeoxycholyl Lysophosphatidylethanolamide (UDCA-LPE) is Associated with Upregulation of Anti-apoptotic Proteins

M Sellinger, D Gotthardt, W Stremmel, W Chamulitrat · Zeitschrift für Gastroenterologie · Ausgabe 01/2012

DOI 10.1055/s-0031-1295877

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Autor:innenM Sellinger, D Gotthardt, W Stremmel, W Chamulitrat
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2012
Jahrgang / SeitenNicht angegeben

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Introduction: An increase of toxic bile acids such as glycochenodeoxycholic acid (GCDCA) frequently occurs in an early phase of liver transplantation. Ischemia during transplantation can cause hepatic cholestasis and damage of intrahepatic biliary epithelial cells. Both stresses contribute to the failure in liver transplantation. We aim to test the effectiveness of UDCA-LPE in inhibition of apoptosis induced by GCDC…

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M Sellinger, D Gotthardt, W Stremmel, W Chamulitrat (2012) Protection against Cholestasis and Ischemia in vitro by Ursodeoxycholyl Lysophosphatidylethanolamide (UDCA-LPE) is Associated with Upregulation of Anti-apoptotic Proteins. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0031-1295877

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