CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Re-programming of Kupffer Cells for immune regulation in response to ConA-induced liver injury
DOI 10.1055/s-0031-1295902
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Autor:innenB Claaß, A Erhardt, G Tiegs
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: In the mouse model of concanavalin A (ConA) induced hepatitis Kupffer cells (KCs) secrete large amounts of hepato-destructive TNFα. Sublethal doses of ConA induce tolerance towards ConA hepatitis in mice within less than two weeks and KCs secrete large amounts of IL–10 upon a second ConA dose. This study is intended to characterize the phenotype of Kupffer cells in ConA tolerant mice. Methods: Liver mo…
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Zitierempfehlung
B Claaß, A Erhardt, G Tiegs (2012) Re-programming of Kupffer Cells for immune regulation in response to ConA-induced liver injury. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0031-1295902
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