CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
The role of the IL–17 axis in a mouse model of drug-induced liver injury
DOI 10.1055/s-0031-1295906
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Autor:innenA Erhardt, T Kessler, G Tiegs
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2012
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Objectives: Acetaminophen (APAP) overdose results in severe liver damage due to hepatocellular necrosis. Injury is triggered by release of pro-inflammatory cytokines and infiltration of immune cells. In this study, we investigated the involvement of the IL–17 axis during drug-induced liver damage. Methods: Primary hepatocytes (HCs) isolated from wildtype (WT), IL17A-, IL17A+F-, or IL23p19-deficient mice were exposed…
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Zitierempfehlung
A Erhardt, T Kessler, G Tiegs (2012) The role of the IL–17 axis in a mouse model of drug-induced liver injury. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0031-1295906
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