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Impact of HBV infection on TGF-β signaling in primary human hepatocytes

J Fabian, S Urban, S Dooley, NM Meindl-Beinker · Zeitschrift für Gastroenterologie · Ausgabe 01/2012

DOI 10.1055/s-0031-1295907

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Autor:innenJ Fabian, S Urban, S Dooley, NM Meindl-Beinker
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2012
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

TGF-β is a profibrotic cytokine playing a pivotal role in cell signaling in liver. Chronical HBV infection leads to fibrosis and often ends in HCC. As TGF-β is frequently upregulated in HBV-infected patients, it is important to elucidate its role in the course of HBV infection. Primary human hepatocytes from 3 donors were infected with HBV. Replication of HBV in infected cells was investigated by HBsAg values in the…

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J Fabian, S Urban, S Dooley, NM Meindl-Beinker (2012) Impact of HBV infection on TGF-β signaling in primary human hepatocytes. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0031-1295907

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