CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
THE ENTRY INHIBITOR MYRCLUDEX-B EFFICIENTLY BLOCKS VIRAL SPREADING IN VIVO IN HUMAN LIVER CHIMERIC uPA/ SCID MICE PREVIOUSLY INFECTED WITH HEPATITIS B VIRUS
DOI 10.1055/s-0031-1295923
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Autor:innenM Lütgehetmann, M M´Barek, T Volz, L Allweiss, M Helbig, A Alexandrov, AW Lohse, J Petersen, S Urban, M Dandri
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Antiviral treatments based on interferon-a or polymerase inhibitors are generally notcurative and additional therapeutic strategies interfering with other HBV replicationsteps are needed. We previously demonstrated prevention of de novo HBV infectionby pre-treating uPA/SCID mice with Myrcludex-B, a lipopeptide derived from the HBVpreS1 domain (Nat. Biotech.2008). Aim of this study was to investigate the abilityof My…
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Zitierempfehlung
M Lütgehetmann, M M´Barek, T Volz, L Allweiss, M Helbig, A Alexandrov, AW Lohse, J Petersen, S Urban, M Dandri (2012) THE ENTRY INHIBITOR MYRCLUDEX-B EFFICIENTLY BLOCKS VIRAL SPREADING IN VIVO IN HUMAN LIVER CHIMERIC uPA/ SCID MICE PREVIOUSLY INFECTED WITH HEPATITIS B VIRUS. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0031-1295923
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