CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
HBV messenger RNA (mRNA) is a strong predictive marker for HBeAg and HBsAg loss during antiviral treatment with nucleoside/nucleotide analogues (NUCs) in patients with chronic hepatitis B virus (HBV) infection
DOI 10.1055/s-0031-1295943
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Autor:innenF van Bömmel, A Bartens, A Mysickova, A Brodzinski, B Fülöp, J Hofmann, D Krüger, T Berg, A Edelmann
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2012
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Aims: Treatment with NUCs can completely suppress HBV DNA levels in most patients, however there are few markers for the prediction of long term response. We studied the association of HBeAg and HBsAg loss with serum levels of circulating full-length (fl) and truncated (tr)HBV mRNA before and during NUC treatment. Methods: For specific detection and quantification of fl and trRNA species, two step real-time reverse…
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Zitierempfehlung
F van Bömmel, A Bartens, A Mysickova, A Brodzinski, B Fülöp, J Hofmann, D Krüger, T Berg, A Edelmann (2012) HBV messenger RNA (mRNA) is a strong predictive marker for HBeAg and HBsAg loss during antiviral treatment with nucleoside/nucleotide analogues (NUCs) in patients with chronic hepatitis B virus (HBV) infection. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0031-1295943
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