CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Partial loss of immunological tolerance in CCR5-deficient mice in the murine model of concanavalin A-induced liver injury
DOI 10.1055/s-0031-1295948
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Autor:innenC Wegscheid, U Panzer, G Tiegs, A Erhardt
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2012
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Introduction: Injection of a sublethal dose of concanavalin A (ConA) induces tolerance against the same agent within one week. Both Tregs and Th1 polarized as well as NKT cells express the chemokine receptor CCR5 and are recruited into the liver by the ligands CCL3/4/5. In this study, the role of CCR5 was investigated during ConA hepatitis and ConA tolerance induction. Methods: C57BL/6 wt and CCR5KO mice were inject…
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Zitierempfehlung
C Wegscheid, U Panzer, G Tiegs, A Erhardt (2012) Partial loss of immunological tolerance in CCR5-deficient mice in the murine model of concanavalin A-induced liver injury. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0031-1295948
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