CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Induction of heme oxygenase 1 by HMG-CoA-Reductase inhibitors interferes with HCV replication
DOI 10.1055/s-0031-1295952
Bibliografische Angaben
Nachweis in CareLit
Autor:innenA Wüstenberg, AD Keller, E Lehmann, H Sirma, R Bartenschlager, V Lohmann, C Loscher, M Dandri, G Tiegs, G Sass
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background and Aims: Heme oxygenase 1 (HO–1) induction or over-expression has been shown to interfere with HCV replication. Induction under experimental conditions is obtained by use of cobalt-protoporphyrin-IX (CoPP), which as a heavy metal compound is not acceptable for patient treatment. We investigated anti-viral as well as HO–1 inducing properties of HMG-CoA reductase inhibitors (statins). Methods: HO–1 inducti…
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Zitierempfehlung
A Wüstenberg, AD Keller, E Lehmann, H Sirma, R Bartenschlager, V Lohmann, C Loscher, M Dandri, G Tiegs, G Sass (2012) Induction of heme oxygenase 1 by HMG-CoA-Reductase inhibitors interferes with HCV replication. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0031-1295952
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