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Naturally occurring, tumor-specific CD8+ T cells in patients with hepatocellular carcinoma display a clear immunodominance

T Flecken, N Schmidt, S Hild, O Drognitz, DA Price, C Neumann-Haefelin, HC Spangenberg, R Thimme · Zeitschrift für Gastroenterologie · Ausgabe 01/2012

DOI 10.1055/s-0031-1295956

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Autor:innenT Flecken, N Schmidt, S Hild, O Drognitz, DA Price, C Neumann-Haefelin, HC Spangenberg, R Thimme
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2012
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide and ranks third in mortality. This is partly due to a limited number of available therapeutic approaches. Since several studies found that the immune response directed against the tumor is associated with prognosis, immunotherapy is a potential future way of treatment. To develop such immune-based therapies, a better understanding of the natura…

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T Flecken, N Schmidt, S Hild, O Drognitz, DA Price, C Neumann-Haefelin, HC Spangenberg, R Thimme (2012) Naturally occurring, tumor-specific CD8+ T cells in patients with hepatocellular carcinoma display a clear immunodominance. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0031-1295956

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