CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Expression of TRAIL receptors and cFLIP correlates with grade of malignancy and survival in patients with hepatocellular carcinoma
DOI 10.1055/s-0031-1295963
Bibliografische Angaben
Nachweis in CareLit
Autor:innenS Brost, T Longerich, U Hinz, R Koschny, J Sykora, E Batke, K Breuhahn, P Schemmer, H Walczak, W Stremmel, P Schirmacher, TM Ganten
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
BACKGROUND AND Aims: TRAIL (TNF-related apoptosis-inducing ligand) induces apoptosis upon binding to TRAIL death receptors TRAIL receptor 1 (TRAIL-R1) and TRAIL-R2. TRAIL-R3 and TRAIL-R4 have no or only a truncated death domain and cannot induce apoptosis. On the contrary, activation of TRAIL-R4 might promote cell survival and proliferation. cFLIP is a potent inhibitor of the extrinsic apoptosis pathway. The anti-tu…
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Zitierempfehlung
S Brost, T Longerich, U Hinz, R Koschny, J Sykora, E Batke, K Breuhahn, P Schemmer, H Walczak, W Stremmel, P Schirmacher, TM Ganten (2012) Expression of TRAIL receptors and cFLIP correlates with grade of malignancy and survival in patients with hepatocellular carcinoma. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0031-1295963
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