CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Smad7 expression is upregulated in HCC patients and correlates with Smad2 mediated downstream signaling in HCC cell lines
DOI 10.1055/s-0031-1295969
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Nachweis in CareLit
Autor:innenJ Dzieran, J Fabian, X Gu, T Weiß, C Gao, S Dooley, NM Meindl-Beinker
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Hepatocellular carcinoma (HCC) is the third most deadliest cancer and very heterogenic. Together with often late diagnosis, this leads to the necessity of new treatment strategies. The TGF-ß family regulates a cohourt of cellular processes. Smad7 is a potent inhibitor of canonical TGF-ß signaling. As TGF-ß may fulfil ambiguous functions, it is important to develop a deep understanding about its tumor suppressive vs.…
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Zitierempfehlung
J Dzieran, J Fabian, X Gu, T Weiß, C Gao, S Dooley, NM Meindl-Beinker (2012) Smad7 expression is upregulated in HCC patients and correlates with Smad2 mediated downstream signaling in HCC cell lines. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0031-1295969
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