CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
The loss of miR–198 is crucial for development and progression of hepatocellular carcinoma
DOI 10.1055/s-0031-1295972
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Autor:innenN Elfimova, A Noetel, M Kwiecinski, N Winkel, KS Ommer, HP Dienes, M Odenthal
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aims: miRNA are small, non-coding RNA molecules regulating gene expression post-transcriptionally. Recently, we have demonstrated that miRNA–198 (miR–198) is significantly down regulated in HCV-positive hepatocellular carcinoma (HCC), affecting markedly cell growth of hepatoma cells. Methods: In order to identify potential pathways of miR–198 function, we transfected hepatoma cells (Huh7) with miR–198. Subsequently,…
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Zitierempfehlung
N Elfimova, A Noetel, M Kwiecinski, N Winkel, KS Ommer, HP Dienes, M Odenthal (2012) The loss of miR–198 is crucial for development and progression of hepatocellular carcinoma. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0031-1295972
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