CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Panobinostat treatment determines oncogenic miRNAs down-regulation in liver cancer cells
DOI 10.1055/s-0031-1295977
Bibliografische Angaben
Nachweis in CareLit
Autor:innenA Henrici, R Montalbano, K Quint, M Ocker, P Di Fazio
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background. miRNAs represent new targets for future cancer therapy due to their tumorigenic and tumorsuppressor activities. In particular, miR–19a, miR–19b–1 and miR–30a promote tumor progression by blocking the translation of proteins related to apoptotic and autophagic cell death like APAF1 and Beclin1 in many solid tumors. We have previously shown that panobinostat, a potent pandeacetylase inhibitor, was able to…
Zitieren
Zitierempfehlung
A Henrici, R Montalbano, K Quint, M Ocker, P Di Fazio (2012) Panobinostat treatment determines oncogenic miRNAs down-regulation in liver cancer cells. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0031-1295977
Mit CareLit weiterarbeiten