CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Selective induction of apoptosis by HMG-CoA-reductase inhibitors in hepatoma cells is dependent on p53 expression
DOI 10.1055/s-0031-1295979
Bibliografische Angaben
Nachweis in CareLit
Autor:innenJ Kah, A Wüstenberg, A Keller, H Sirma, G Tiegs, G Sass, M Dandri
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background and Aims: HMG-CoA-reductase-inhibitors (statins) are widely used drugs to interfere with cholesterol biosynthesis. Besides this usage, evidence increases that statins might also be useful in therapy of viral infections or cancer. We investigated the effects of statins on primary mouse and human hepatocytes as well as mouse (Hepa1–6) and human (Huh7, HepG2, Hep3B) hepatoma cell lines. Methods: Effects of f…
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Zitierempfehlung
J Kah, A Wüstenberg, A Keller, H Sirma, G Tiegs, G Sass, M Dandri (2012) Selective induction of apoptosis by HMG-CoA-reductase inhibitors in hepatoma cells is dependent on p53 expression. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0031-1295979
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