CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
TGR5 (Gpbar–1) is expressed in cholangiocarcinomas and confers apopotosis resistance in isolated cholangiocytes
DOI 10.1055/s-0031-1295980
Bibliografische Angaben
Nachweis in CareLit
Autor:innenV Keitel, R Reinehr, M Reich, A Sommerfeld, K Cupisti, WT Knoefel, D Häussinger
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Cholangiocarcinomas (CCA) are malignancies of the biliary tract with limited treatment options. The molecular mechanisms leading to the development of CCA are unknown, however, chronic inflammation and elevated bile acid levels have been implicated in the pathogenesis of CCA. TGR5 is a membrane-bound bile acid receptor, which is expressed in cholangiocytes. Aim of the present study was to analyze the expression of T…
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Zitierempfehlung
V Keitel, R Reinehr, M Reich, A Sommerfeld, K Cupisti, WT Knoefel, D Häussinger (2012) TGR5 (Gpbar–1) is expressed in cholangiocarcinomas and confers apopotosis resistance in isolated cholangiocytes. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0031-1295980
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