CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
p53, p63, p73 and the mitochondrial apoptosis signaling pathway in human hepatocellular carcinoma (HCC)
DOI 10.1055/s-0031-1295984
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Nachweis in CareLit
Autor:innenL Koenig, M Soboletzki, M Mainhard, W Stremmel, M Müller
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
In addition to their functions as nuclear transcription factors p53 and its family members can act in the cytosol and mitochondria to promote apoptosis through transcription-independent mechanisms, including direct protein-protein interactions (PPI) with various members of the Bcl–2 family. Targeting transcription-independent p53 family-mediated cell death may provide a promising strategy for p53-based cancer therap…
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Zitierempfehlung
L Koenig, M Soboletzki, M Mainhard, W Stremmel, M Müller (2012) p53, p63, p73 and the mitochondrial apoptosis signaling pathway in human hepatocellular carcinoma (HCC). Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0031-1295984
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