CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Treatment of hepatocellular carcinoma with a novel suicide gene-expressing oncolytic measles vaccine virus
DOI 10.1055/s-0031-1295985
Bibliografische Angaben
Nachweis in CareLit
Autor:innenJ Lampe, S Bossow, I Smirnow, W Timo, W Neubert, NP Malek, M Bitzer, UM Lauer
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Oncolytic viruses are promising agents under investigation as cancer therapeutics. These replication competent viruses selectively infect and kill cancer cells. However, early clinical results point out that oncolysis achieved by unmodified vectors seems to be not sufficiently effective. To enhance cell killing, oncolytic viruses can be engineered to express suicide genes which convert non-toxic substa…
Zitieren
Zitierempfehlung
J Lampe, S Bossow, I Smirnow, W Timo, W Neubert, NP Malek, M Bitzer, UM Lauer (2012) Treatment of hepatocellular carcinoma with a novel suicide gene-expressing oncolytic measles vaccine virus. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0031-1295985
Mit CareLit weiterarbeiten