CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Antitumor efficacy of the c-met inhibitor tivantinib (ARQ–197) in liver cancer cells: effects on apoptosis and cell cycle
DOI 10.1055/s-0031-1295987
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Nachweis in CareLit
Autor:innenS Lü, A Rizzani, FT Kolligs, B Göke, A Gerbes, EN De Toni
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: c-met has become a promising therapeutic target in cancer therapy due to its prognostic significance and its important role in determining the metastatic properties of solid tumors. Tivantinib (ARQ–197) is a novel selective small molecule inhibitor of c-Met which is undergoing clinical investigation in several tumor entities.Aims and methods: we explored the effects of tivantinib on hepatocellular carcin…
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Zitierempfehlung
S Lü, A Rizzani, FT Kolligs, B Göke, A Gerbes, EN De Toni (2012) Antitumor efficacy of the c-met inhibitor tivantinib (ARQ–197) in liver cancer cells: effects on apoptosis and cell cycle. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0031-1295987
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