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Expression of prospero-related homeobox 1 (prox–1) transcription factor and epithelial adhesion molecule (EpCAM) in a rat model of intrahepatic cholangiocarcinogenesis

N Naz, IA Mailk, F Schultz, T Mansuroglu, G Ramadori · Zeitschrift für Gastroenterologie · Ausgabe 01/2012

DOI 10.1055/s-0031-1295997

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Autor:innenN Naz, IA Mailk, F Schultz, T Mansuroglu, G Ramadori
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2012
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Deregulation of homeobox genes may give rise to tumorigenesis in target organs (1). Immuhistochemical studies have shown that the Prospero-related homeobox 1 (Prox–1) gene is expressed in mature hepatocytes but is not detectable in non-parenchymal liver cells (2). EpCAM is a surface marker on human hepatic stem/progenitor cells that is reported as absent on mature hepatocytes.However, hepatocytes (that have recently…

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N Naz, IA Mailk, F Schultz, T Mansuroglu, G Ramadori (2012) Expression of prospero-related homeobox 1 (prox–1) transcription factor and epithelial adhesion molecule (EpCAM) in a rat model of intrahepatic cholangiocarcinogenesis. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0031-1295997

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