CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Breaking tumor resistances by broad spectrum assessment of virotherapeutic resistance phenomena
DOI 10.1055/s-0031-1295999
Bibliografische Angaben
Nachweis in CareLit
Autor:innenM Noll, S Berchtold, J Lampe, NP Malek, M Bitzer, UM Lauer
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Measles vaccine virus (MeV) has proven its oncolytic potential in tumor models and early clinical trials, but primary and secondary resistances often emerge. In order to increase efficiency and to overcome resistance phenomena, a recombinant suicide gene armed MeV vaccine strain (MeV-SCD) was generated, converting the non-toxic prodrug 5-fluorocytosine (5-FC) into the cytotoxic compound 5-fluorouracil…
Zitieren
Zitierempfehlung
M Noll, S Berchtold, J Lampe, NP Malek, M Bitzer, UM Lauer (2012) Breaking tumor resistances by broad spectrum assessment of virotherapeutic resistance phenomena. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0031-1295999
Mit CareLit weiterarbeiten